Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312527 | 0.98 | SIGMAR1 (0.71) | SIGMAR1L3MBTL1ALDH1A1HPGDKMT2A | |
| SCHEMBL255309 | 0.92 | SIGMAR1 (0.70) | SIGMAR1KMT2A | |
| SCHEMBL14415413 | 0.90 | SIGMAR1 (0.70) | SIGMAR1 | |
| SCHEMBL19505653 | 0.84 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL19505477 | 0.84 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL1148376 | 0.84 | SIGMAR1 (0.68) | SIGMAR1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14415412 | 0.83 | SIGMAR1 (0.53) | SIGMAR1L3MBTL1 | |
| SCHEMBL15131171 | 0.81 | SIGMAR1 (0.65) | SIGMAR1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8099627 | 0.81 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL28702566 | 0.81 | SIGMAR1 (0.62) | SIGMAR1L3MBTL1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314314-B1 | Filled compositions | DOW CORNING SA (BE) | 1994-08-24 | — | — | EP | disclosed |
| US-5073586-A | Polysiloxane, carbonate, alkylsulfonate, low modulus | DOW CORNING S.A. (BE) | 1991-12-17 | — | — | US | disclosed |
| EP-0314314-A2 | Filled compositions | DOW CORNING S.A. (BE) | 1989-05-03 | — | — | EP | disclosed |