Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351364 | 0.97 | KDM1A (0.33) | KDM1AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9347527 | 0.91 | HDAC3 (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL49259 | 0.82 | KDM1A (0.34) | KDM1AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL14765571 | 0.79 | — | — | |
| SCHEMBL11495832 | 0.79 | — | — | |
| SCHEMBL11495833 | 0.79 | — | — | |
| SCHEMBL9350743 | 0.78 | — | — | |
| SCHEMBL1966089 | 0.78 | — | — | |
| SCHEMBL9751277 | 0.78 | — | — | |
| SCHEMBL9882026 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376666-A | Hypotensive agents, angiotension antagonist, enzyme inhibitors , treating congestive heart failure | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-12-27 | — | — | US | disclosed |
| US-4677166-A | Halogenated ethylene random copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0181222-A2 | Halogenated ethylene random copolymer and process for making it | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |