Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49444 | 0.91 | HDAC3 (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9350737 | 0.82 | KDM1A (0.34) | KDM1AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9351364 | 0.80 | KDM1A (0.33) | KDM1AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9350743 | 0.78 | — | — | |
| SCHEMBL1966089 | 0.78 | — | — | |
| SCHEMBL5807457 | 0.78 | — | — | |
| SCHEMBL9751277 | 0.78 | — | — | |
| SCHEMBL9882026 | 0.78 | — | — | |
| SCHEMBL9351369 | 0.76 | — | — | |
| SCHEMBL9751195 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150266839-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-09-24 | — | — | US | disclosed |
| US-20150225392-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-13 | — | — | US | disclosed |
| US-9072758-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| US-9040525-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-8765752-B2 | 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-2703394-A1 | NOVEL 3-HYDROXYISOTHIAZOLE 1-OXIDE DERIVATIVE | Mochida Pharmaceutical Co., Ltd. (JP) | 2014-03-05 | — | — | EP | disclosed |
| EP-2703393-A1 | CYCLIC AMIDE DERIVATIVE | Mochida Pharmaceutical Co., Ltd. (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20140057871-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-02-27 | — | — | US | disclosed |
| US-8629102-B2 | 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-8557766-B2 | 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-15 | — | — | US | disclosed |
| US-8013052-B2 | Curable resin, production method thereof, epoxy resin composition, and electronic device | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090062460-A1 | CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE | HITACHI CHEMICAL CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090023855-A1 | NOVEL CURABLE RESIN, PRODUCTION METHOD THEREOF, EPOXY RESIN COMPOSITION, AND ELECTRONIC DEVICE | RESONAC CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| US-7250211-B1 | Polypropylene films and multilayered laminate | IDEMITSU KOSAN CO., LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| EP-1231226-B1 | CALENDERED OR INJECTION MOLDED ARTICLE OUT OF POLYPROPYLENE | IDEMITSU KOSAN CO (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6770355-B1 | USABLE AS A SUBSTITUTE FOR SOFT VINYL CHLORIDE FILMS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| US-6734270-B1 | Polypropylene-based calendered article and injection-molded article | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-05-11 | — | — | US | disclosed |
| EP-1241206-A1 | POLYPROPYLENE FILM AND MULTILAYERED LAMINATE | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1231226-A1 | ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1231236-A1 | POLYPROPYLENE FILM AND MULTILAYERED LAMINATE | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266839-A1 | CYCLIC AMIDE DERIVATIVE | GPR119, NR0B1, NR4A1 | KDM1A 1720/4885HDAC4 887/4885HDAC2 1466/4885 |
| US-20140057871-A1 | CYCLIC AMIDE DERIVATIVE | GPR119, NR0B1, NR4A1 | KDM1A 1650/4885HDAC4 854/4885HDAC2 1465/4885 |
| US-20150225392-A1 | CYCLIC AMIDE DERIVATIVE | GPR119, NR0B1, NR2C2 | KDM1A 2428/4885HDAC4 735/4885HDAC2 769/4885 |
| US-20090062460-A1 | CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE | NCAPH, RAD51, H1-2 | KDM1A 368/4885HDAC4 1312/4885HDAC2 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.