Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347677 | 1.00 | RAB9A (0.51) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9351372 | 1.00 | RAB9A (0.51) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9351935 | 1.00 | RAB9A (0.51) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10691339 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10692467 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9436296 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9351433 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9347849 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10692843 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9436027 | 0.89 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-4871469-A | TRIFLUOROTOLUENE DERIVATIVES | BESCRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0264435-A1 | SMECTIC LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1988-04-27 | — | — | EP | disclosed |
| WO-1987006602-A1 | SMECTIC LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-11-05 | — | — | WO | disclosed |