⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1059003 | 0.47 | — | — | |
| SCHEMBL11798711 | 0.47 | — | — | |
| SCHEMBL7790096 | 0.47 | — | — | |
| SCHEMBL1446428 | 0.47 | — | — | |
| Methane SCHEMBL11799024 | 0.45 | — | — | |
| SCHEMBL6689915 | 0.39 | — | — | |
| SCHEMBL8600614 | 0.39 | — | — | |
| SCHEMBL64228 | 0.39 | — | — | |
| Water SCHEMBL11399021 | 0.36 | — | — | |
| SCHEMBL1191040 | 0.32 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324184-B1 | 2-Amino-1,2,3,4-tetrahydroisoquinoline derivatives, method for their preparation and their use as medicines | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-09-28 | — | — | EP | disclosed |
| EP-0324988-B1 | 4-CHLOR-3-SULFAMOYL BENZOIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, MEDICINES CONTAINING THEM AND USE OF THESE COMPOUNDS IN THE PREPARATION OF DIURETIC AND SALT REDUCING ACTIVITY MEDICINES | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-04-29 | — | — | EP | disclosed |
| US-4940716-A | 2-amino-tetrahydro-isoquinolene derivatives and a process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1990-07-10 | — | — | US | disclosed |
| EP-0324988-A1 | 4-Chlor-3-sulfamoyl benzoic acid hydrazides, process for their preparation, medicines containing them and use of these compounds in the preparation of diuretic and salt reducing activity medicines | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1989-07-26 | — | — | EP | disclosed |