Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353009 | 0.94 | CHRM2 (0.47) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9352895 | 0.89 | CHRM2 (0.49) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| Fumaric Acid SCHEMBL9357096 | 0.84 | CHRM2 (0.58) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9353113 | 0.84 | SLC6A2 (0.50) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9353307 | 0.84 | SLC6A3 (0.52) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9353045 | 0.83 | CHRM2 (0.47) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9353460 | 0.82 | CHRM2 (0.50) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL10436005 | 0.81 | MAPK1 (0.49) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9356763 | 0.81 | SLC6A2 (0.57) | SLC6A2CHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL9353122 | 0.80 | CHRM2 (0.53) | SLC6A2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399414-B1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5153207-A | Antihistamine and antiallergic agent | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0399414-A1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |