Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254317 | 0.88 | BCHE (0.59) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL14282951 | 0.88 | BCHE (0.54) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL9356588 | 0.87 | BCHE (0.58) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL9357015 | 0.87 | BCHE (0.51) | BCHECHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL4021861 | 0.86 | CHRM2 (0.63) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL14282953 | 0.84 | BCHE (0.59) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL9353013 | 0.84 | BCHE (0.64) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL14282927 | 0.83 | BACE1 (0.52) | SLC6A2SLC6A3NPC1LMNASLC6A4 | |
| SCHEMBL4255064 | 0.83 | TSHR (0.59) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL9356762 | 0.83 | MAPK1 (0.60) | BCHECHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399414-B1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5153207-A | Antihistamine and antiallergic agent | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0399414-A1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |