Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664705 | 0.90 | CCR5 (0.46) | BACE1NPY2RALDH1A1KDM4E | |
| SCHEMBL14282940 | 0.87 | ALDH1A1 (0.52) | NPY2RALDH1A1KDM4ELMNA | |
| SCHEMBL7359674 | 0.86 | ALDH1A1 (0.55) | BACE1NPY2RALDH1A1KDM4ETSHR | |
| SCHEMBL9353069 | 0.83 | BCHE (0.56) | LMNANPC1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL3662230 | 0.83 | BACE1 (0.58) | BACE1KDM4ETSHRNPC1 | |
| SCHEMBL14198379 | 0.82 | TSHR (0.63) | NPY2RALDH1A1KDM4ETSHRGAA | |
| SCHEMBL27622744 | 0.81 | SLC18A3 (0.59) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3391962 | 0.80 | CACNA2D1 (0.61) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL824216 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL11795167 | 0.79 | SLC6A4 (0.56) | BACE1ALDH1A1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |