Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518578 | 0.91 | LMNA (0.46) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL1421055 | 0.83 | CARM1 (0.56) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11590368 | 0.83 | CYP2D6 (0.52) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11590369 | 0.83 | CYP2D6 (0.52) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL1518347 | 0.79 | POLB (0.46) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL1070499 | 0.79 | LMNA (0.41) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11591843 | 0.77 | CYP2D6 (0.47) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11591841 | 0.77 | CYP2D6 (0.47) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11593227 | 0.76 | MEN1 (0.43) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11593229 | 0.76 | MEN1 (0.43) | LMNAGBA1CYP1A2CYP2D6CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532644-B1 | ANTITUSSIVE AND MUCUS REGULATING AGENT, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | MEDIOLANUM FARMACEUTICI SRL (IT) | 1994-10-19 | — | — | EP | claimed |