Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357098 | 1.00 | ACE (0.72) | ACE | |
| SCHEMBL9353341 | 1.00 | ACE (0.72) | ACE | |
| SCHEMBL9353336 | 1.00 | ACE (0.72) | ACE | |
| SCHEMBL9353188 | 1.00 | ACE (0.72) | ACE | |
| SCHEMBL9353595 | 0.99 | ACE (0.73) | ACE | |
| SCHEMBL9353704 | 0.85 | ACE (0.98) | ACE | |
| SCHEMBL9353553 | 0.85 | ACE (0.98) | ACE | |
| Ceronapril SCHEMBL121163 | 0.84 | ACE (1.00) | ACE | |
| Ceronapril SCHEMBL121164 | 0.84 | ACE (1.00) | ACE | |
| Ceronapril SCHEMBL1649023 | 0.84 | ACE (1.00) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350138-B1 | Processes for preparing phosphonyl hydroxyacyl prolines | SQUIBB & SONS INC (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0350138-A2 | Processes for preparing phosphonyl hydroxyacyl prolines | E.R. SQUIBB & SONS, INC. (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4745196-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0229520-A1 | Orally active phosphonyl hydroxyacyl prolines and processes for preparing phosphonyl hydroxyacyl prolines | E.R. Squibb & Sons, Inc. (US) | 1987-07-22 | — | — | EP | disclosed |