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SCHEMBL9353188

SCHEMBL9353188

CCCCCCP(=O)(O)O[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9353177 1.00 ACE (0.72) ACE
SCHEMBL9357098 1.00 ACE (0.72) ACE
SCHEMBL9353341 1.00 ACE (0.72) ACE
SCHEMBL9353336 1.00 ACE (0.72) ACE
SCHEMBL9353595 0.99 ACE (0.73) ACE
SCHEMBL9353704 0.85 ACE (0.98) ACE
SCHEMBL9353553 0.85 ACE (0.98) ACE
Ceronapril SCHEMBL121163 0.84 ACE (1.00) ACE
Ceronapril SCHEMBL121164 0.84 ACE (1.00) ACE
Ceronapril SCHEMBL1649023 0.84 ACE (1.00) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350138-B1 Processes for preparing phosphonyl hydroxyacyl prolines SQUIBB & SONS INC (US) 1994-10-19 — — EP disclosed
EP-0350138-A2 Processes for preparing phosphonyl hydroxyacyl prolines E.R. SQUIBB & SONS, INC. (US) 1990-01-10 — — EP disclosed
US-4745196-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1988-05-17 — — US disclosed
EP-0229520-A1 Orally active phosphonyl hydroxyacyl prolines and processes for preparing phosphonyl hydroxyacyl prolines E.R. Squibb & Sons, Inc. (US) 1987-07-22 — — EP disclosed
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