Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.77 |
| ▸ | ATG7 | O95352 | 1/20 | 0.77 |
| ▸ | UBA7 | P41226 | 1/20 | 0.77 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.77 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.77 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010400 | 1.00 | UBA6 (0.77) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL31670659 | 1.00 | UBA6 (0.77) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL10699521 | 1.00 | UBA6 (0.77) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL10699536 | 1.00 | UBA6 (0.77) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL10944136 | 1.00 | UBA6 (0.77) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL9353260 | 1.00 | UBA6 (0.77) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL10869781 | 0.95 | — | — | |
| SCHEMBL10600546 | 0.95 | — | — | |
| SCHEMBL10604673 | 0.95 | — | — | |
| SCHEMBL10599606 | 0.92 | UBA6 (0.75) | UBA6ATG7UBA7NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4693996-A | SYNERGISTIC MIXTURE OF IMIDAZOLYL-PHENYL-PYRIDAZINONE AND INDANYL-ADENOSINE | WARNER-LAMBERT COMPANY (US) | 1987-09-15 | — | — | US | claimed |
| EP-0378518-B1 | Adenosine derivatives having pharmaceutical activity as antihypertensives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-09-28 | — | — | EP | disclosed |
| EP-0378518-A2 | Adenosine derivatives having pharmaceutical activity as antihypertensives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-07-18 | — | — | EP | disclosed |
| US-4693996-A | SYNERGISTIC MIXTURE OF IMIDAZOLYL-PHENYL-PYRIDAZINONE AND INDANYL-ADENOSINE | WARNER-LAMBERT COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0181129-A2 | N6-substituted deoxyribose analogs of adenosines | WARNER-LAMBERT COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |