Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9357076 | 0.99 | CARM1 (0.47) | CARM1PRMT6FFAR1FFAR4NAAA | |
| Fumaric Acid SCHEMBL9353194 | 0.95 | CARM1 (0.45) | CARM1PRMT6FFAR1FFAR4NAAA | |
| SCHEMBL9353024 | 0.90 | FFAR1 (0.49) | CARM1PRMT6FFAR1FFAR4PPARG | |
| SCHEMBL9353365 | 0.89 | CARM1 (0.50) | CARM1PRMT6FFAR1FFAR4HTR7 | |
| Hydrochloric Acid SCHEMBL9353016 | 0.88 | CARM1 (0.49) | CARM1PRMT6FFAR1FFAR4HTR7 | |
| SCHEMBL9353119 | 0.88 | CARM1 (0.47) | CARM1PRMT6FFAR1FFAR4NAAA | |
| Hydrochloric Acid SCHEMBL9353186 | 0.88 | CARM1 (0.48) | CARM1PRMT6FFAR1FFAR4HTR7 | |
| Hydrochloric Acid SCHEMBL9352889 | 0.88 | CARM1 (0.48) | CARM1PRMT6FFAR1FFAR4HTR7 | |
| Hydrochloric Acid SCHEMBL9356729 | 0.87 | CARM1 (0.46) | CARM1PRMT6FFAR1FFAR4NAAA | |
| Hydrochloric Acid SCHEMBL9352951 | 0.87 | CARM1 (0.47) | CARM1PRMT6FFAR1FFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399414-B1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5153207-A | Antihistamine and antiallergic agent | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0399414-A1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |