SCHEMBL9353365

SCHEMBL9353365

Cc1ccc(-c2ccccc2COC2CCN(C(C)C(=O)O)CC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 2/20 0.43
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
HTR7 P34969 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SCN1A P35498 2/20 0.37
SCN2A Q99250 2/20 0.37
SCN3A Q9NY46 2/20 0.37
P2RX7 Q99572 2/20 0.37
PTGIR P43119 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9353016 0.99 CARM1 (0.49) CARM1PRMT6FFAR1FFAR4KMT2A
SCHEMBL9353290 0.89 CARM1 (0.48) CARM1PRMT6FFAR1FFAR4KMT2A
Hydrochloric Acid SCHEMBL9353186 0.89 CARM1 (0.48) CARM1PRMT6FFAR1FFAR4KMT2A
Hydrochloric Acid SCHEMBL9352889 0.89 CARM1 (0.48) CARM1PRMT6FFAR1FFAR4KMT2A
Hydrochloric Acid SCHEMBL9357076 0.89 CARM1 (0.47) CARM1PRMT6FFAR1FFAR4KMT2A
Hydrochloric Acid SCHEMBL9352951 0.89 CARM1 (0.47) CARM1PRMT6FFAR1FFAR4KMT2A
Hydrochloric Acid SCHEMBL9353346 0.88 CARM1 (0.47) CARM1PRMT6FFAR1FFAR4KMT2A
SCHEMBL9353024 0.88 FFAR1 (0.49) CARM1PRMT6FFAR1FFAR4KMT2A
SCHEMBL9353420 0.87 CARM1 (0.48) CARM1PRMT6FFAR1FFAR4KMT2A
Hydrochloric Acid SCHEMBL9356747 0.86 CARM1 (0.47) CARM1PRMT6FFAR1FFAR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399414-B1 Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same HOKURIKU PHARMACEUTICAL (JP) 1994-09-21 EP disclosed
US-5153207-A Antihistamine and antiallergic agent HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1992-10-06 US disclosed
EP-0399414-A1 Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1990-11-28 EP disclosed