Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TK1 | P04183 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789521 | 0.88 | LMNA (0.44) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL29803038 | 0.85 | LMNA (0.42) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL5193538 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL27041390 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL22978936 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL29230391 | 0.81 | LMNA (0.43) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL10898979 | 0.80 | LMNA (0.42) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL10902342 | 0.80 | POLA1 (0.44) | — | |
| SCHEMBL10903331 | 0.79 | LMNA (0.42) | LMNASMN1; SMN2DNMT1BLMPMP22 | |
| SCHEMBL29165631 | 0.78 | LMNA (0.41) | LMNASMN1; SMN2TK1ADRB1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225807-B1 | Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein | CHIRON CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| US-4587044-A | Linkage of proteins to nucleic acids | THE JOHNS HOPKINS UNIVERSITY (US) | 1986-05-06 | — | — | US | disclosed |