Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935655 | 0.90 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL935671 | 0.83 | PIK3CD (0.51) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL4413968 | 0.79 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3R2ABCB11TBXA2R | |
| SCHEMBL12688802 | 0.79 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3R2ABCB11TBXA2R | |
| SCHEMBL179580 | 0.79 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3R2ABCB11TBXA2R | |
| SCHEMBL17338341 | 0.78 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL21389745 | 0.77 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL16584856 | 0.77 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3R2PIK3R1PIK3CA | |
| SCHEMBL16356359 | 0.76 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R2ABCB11TBXA2R | |
| SCHEMBL17338292 | 0.74 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3R2PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456444-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011008302-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2011-01-20 | — | — | WO | disclosed |