Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354174 | 0.78 | JAK2 (0.37) | KMT2A | |
| SCHEMBL9354404 | 0.76 | TYMP (0.37) | TYMPALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL9354182 | 0.74 | TYMP (0.53) | TYMPALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL9358047 | 0.73 | TYMP (0.50) | TYMPALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1445690 | 0.68 | TYMP (0.56) | TYMPALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL4560425 | 0.68 | TYMP (0.56) | TYMPALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL9353995 | 0.68 | TYMP (0.54) | TYMPALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL7757620 | 0.67 | TYMP (0.41) | TYMPALDH1A1 | |
| SCHEMBL16315851 | 0.65 | TYMP (0.39) | TYMPALDH1A1 | |
| SCHEMBL14341829 | 0.65 | TYMP (0.39) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515464-B1 | PROCESS FOR PREPARING URACIL DERIVATIVES | ERBA CARLO SPA (IT) | 1994-10-19 | — | — | EP | disclosed |
| US-5286861-A | Process for preparing uracil derivatives | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-02-15 | — | — | US | disclosed |