Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15971081 | 0.81 | KDM4E (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15970972 | 0.71 | KDM4E (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3747639 | 0.69 | KDM4E (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6261673 | 0.69 | HPGD (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30405202 | 0.68 | FABP4 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8741171 | 0.67 | HPGD (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL434941 | 0.67 | CYP19A1 (0.56) | POLBHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL15431762 | 0.67 | BACE1 (0.43) | CA12CA9HSD17B10ALDH1A1KDM4E | |
| SCHEMBL2317348 | 0.66 | TSHR (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18567358 | 0.66 | BACE1 (0.44) | CA12CA9HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341990-B1 | Cephalosporins, process for their preparation and pharmaceutical compositions | ICI PLC (GB) | 1994-11-09 | — | — | EP | disclosed |
| US-5008259-A | Antibiotics active against strains of Pseudomonas and stable to beta-lactamase | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-16 | — | — | US | disclosed |
| EP-0341990-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-15 | — | — | EP | disclosed |