SCHEMBL9354563

SCHEMBL9354563

Nc1ccc(C=Cc2ccc(S(=O)(=O)O)cc2)c(S(=O)(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
NT5E P21589 2/20 0.50
SENP3 Q9H4L4 4/20 0.45
SENP2 Q9HC62 4/20 0.45
SENP1 Q9P0U3 4/20 0.45
SUMO2 P61956 3/20 0.45
SUMO1 P63165 3/20 0.45
SENP7 Q9BQF6 3/20 0.45
RAD1 O60671 1/20 0.42
P2RY6 Q15077 1/20 0.42
TDP1 Q9NUW8 3/20 0.42
HTR2A P28223 4/20 0.41
HTR2C P28335 4/20 0.41
KCNH2 Q12809 2/20 0.41
CYP19A1 P11511 3/20 0.41
HSD17B10 Q99714 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.41
ENPP2 Q13822 1/20 0.40
NSD2 O96028 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9354557 1.00 ALDH1A1 (0.50) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL30010201 0.94 RAD1 (0.46) ALDH1A1SENP3SENP2SENP1SUMO2
SCHEMBL5770400 0.92 CYP19A1 (0.49) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL5770397 0.92 CYP19A1 (0.49) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL27866774 0.91 ALDH1A1 (0.50) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL14254892 0.89 RAD1 (0.43) ALDH1A1SENP3SENP2SENP1SUMO2
SCHEMBL602305 0.89 RAD1 (0.50) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL30010767 0.89 RAD1 (0.50) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL5858441 0.89 RAD1 (0.50) ALDH1A1TSHRNT5ESENP3SENP2
SCHEMBL38872 0.87 RAD1 (0.51) ALDH1A1TSHRNT5ESENP3SENP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0474039-B1 Ortho-aminoazo compounds BAYER AG (DE) 1994-11-09 EP disclosed
US-5183881-A Chemical intermediate for metallized dyes BAYER AKTIENGESELLSCHAFT (DE) 1993-02-02 US disclosed
EP-0474039-A1 Ortho-aminoazo compounds BAYER AG (DE) 1992-03-11 EP disclosed