Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | GRK6 | P43250 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921188 | 0.84 | MAPT (0.52) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL2462677 | 0.79 | MAPT (0.54) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL2463193 | 0.72 | MAPT (1.00) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL3273424 | 0.71 | MAPT (0.97) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL2464584 | 0.71 | L3MBTL1 (0.74) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL10813018 | 0.70 | CYP1A1 (0.70) | MAPTMAPK1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7769609 | 0.70 | ADORA2A (0.62) | MAPTMAPK1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8983801 | 0.70 | MEN1 (0.63) | MAPTMAPK1L3MBTL1ALDH1A1ALOX12 | |
| SCHEMBL11672943 | 0.70 | ADORA2A (0.59) | MAPTMAPK1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10808664 | 0.70 | MEN1 (0.62) | MAPTMAPK1L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357783-B1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0357783-A1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |