⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354678 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL9354538 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL9655855 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL15738590 | 0.73 | — | — | |
| SCHEMBL9657194 | 0.66 | — | — | |
| SCHEMBL9655750 | 0.66 | TSHR (0.50) | — | |
| SCHEMBL17247994 | 0.66 | — | — | |
| SCHEMBL9658416 | 0.65 | — | — | |
| SCHEMBL13641772 | 0.64 | — | — | |
| SCHEMBL11043238 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322945-B1 | Modification of (co)polymers employing organic peroxides | AKZO NOBEL NV (NL) | 1994-11-02 | — | — | EP | claimed |
| US-5037892-A | Epoxidation Of Olefin Polymers | AKZO N.V. (NL) | 1991-08-06 | — | — | US | claimed |
| EP-0322945-A1 | Modification of (co)polymers employing organic peroxides | Akzo Nobel N.V. (NL) | 1989-07-05 | — | — | EP | claimed |
| EP-0322945-B1 | Modification of (co)polymers employing organic peroxides | AKZO NOBEL NV (NL) | 1994-11-02 | — | — | EP | disclosed |
| US-5202386-A | Adhesion to polar material | AKZO NV (NL) | 1993-04-13 | — | — | US | disclosed |
| US-5037892-A | Epoxidation Of Olefin Polymers | AKZO N.V. (NL) | 1991-08-06 | — | — | US | disclosed |
| EP-0322945-A1 | Modification of (co)polymers employing organic peroxides | Akzo Nobel N.V. (NL) | 1989-07-05 | — | — | EP | disclosed |