SCHEMBL9355162

SCHEMBL9355162

Cc1ccccc1NNc1ccccc1C

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.62
KDM4E B2RXH2 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
MAPT P10636 2/20 0.59
HTT P42858 1/20 0.59
ALDH1A1 P00352 2/20 0.58
POLB P06746 2/20 0.58
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
TSHR P16473 1/20 0.53
ACHE P22303 1/20 0.53
HPGD P15428 3/20 0.52
P2RX7 Q99572 5/20 0.46
CRHR1 P34998 1/20 0.44
SIGMAR1 Q99720 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869240 0.87 ALDH1A1 (0.57) GAAKDM4ETDP1MAPTHTT
SCHEMBL2467696 0.86 GAA (0.56) GAAKDM4ETDP1MAPTHTT
SCHEMBL21876496 0.84 GAA (0.54) GAAKDM4ETDP1MAPTHTT
SCHEMBL1997897 0.84 GAA (0.54) GAAKDM4ETDP1MAPTHTT
Hydrochloric Acid SCHEMBL10693971 0.84 GAA (0.54) GAAKDM4ETDP1MAPTHTT
SCHEMBL6768181 0.83 GAA (0.48) GAAKDM4ETDP1MAPTHTT
Hydrochloric Acid SCHEMBL18172098 0.82 GAA (0.52) GAAKDM4ETDP1MAPTHTT
Hydrochloric Acid SCHEMBL18172145 0.82 GAA (0.52) GAAKDM4ETDP1MAPTHTT
SCHEMBL29511793 0.81 HTT (0.59) GAAKDM4ETDP1MAPTHTT
SCHEMBL183017 0.81 HTT (0.59) GAAKDM4ETDP1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327773-B1 Polysiloxazanes, process for producing same and their use as precursors for ceramics and ceramic materials ATOCHEM ELF SA (FR) 1994-11-02 EP claimed
US-5010158-A Process for preparing polysiloxazane compositions and the products formed thereby ATOCHEM (FR) 1991-04-23 US claimed
CN-118852331-A Chemical conjugates of Evan's blue derivatives and their use as radiation therapies and imaging agents for targeting prostate cancer 美国政府健康及人类服务部 2024-10-29 CN disclosed
CN-111741751-B Chemical conjugates of Evan's blue derivatives and their use as radiation therapies and imaging agents for targeting prostate cancer 美国政府健康及人类服务部 2024-06-28 CN disclosed
EP-4330442-A1 ACTIVATION OF SELF-PASSIVATING METALS USING REAGENT COATINGS FOR LOW TEMPERATURE NITROCARBURIZATION IN THE PRESENCE OF OXYGEN-CONTAINING GAS Swagelok Company (US) 2024-03-06 EP disclosed
WO-2023235668-A1 LASER-ASSISTED REAGENT ACTIVATION AND PROPERTY MODIFICATION OF SELF-PASSIVATING METALS SWAGELOK COMPANY (US) 2023-12-07 WO disclosed
EP-4182033-A1 ISOLATED GENE CODING FOR THE ENZYME GLYCOSYL TRANSFERASE 2 FROM PYROCOCCUS HORIKOSHII OT3 OR ITS HOMOLOGS FROM HYPERTHERMOPHILIC ARCHAEA, HOST CELL EXPRESSING IT AND ITS USE IN A PROCESS FOR PRODUCING SULFATED GLYCOSAMINOGLYCANS Université de Rennes (FR) 2023-05-24 EP disclosed
WO-2022232340-A1 ACTIVATION OF SELF-PASSIVATING METALS USING REAGENT COATINGS FOR LOW TEMPERATURE NITROCARBURIZATION IN THE PRESENCE OF OXYGEN-CONTAINING GAS SWAGELOK COMPANY (US) 2022-11-03 WO disclosed
EP-4069880-A1 CHEMICAL ACTIVATION OF SELF-PASSIVATING METALS Swagelok Company (US) 2022-10-12 EP disclosed
CN-110590596-B Preparation method of 4,4' -diamino-2, 2' -dimethyl-1, 1' -biphenyl 常州市阳光药业有限公司 2022-03-22 CN disclosed
WO-2022056087-A2 LOW-TEMPERATURE CASE HARDENING OF ADDITIVE MANUFACTURED ARTICLES AND MATERIALS AND TARGETED APPLICATION OF SURFACE MODIFICATION SWAGELOK COMPANY (US) 2022-03-17 WO disclosed
US-4919808-A Semipermeable membrane compositions ALLIED-SIGNAL INC. (US) 1990-04-24 US disclosed
EP-0304239-A1 Reformed polysilazane and method of producing same TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1989-02-22 EP disclosed
US-4550207-A Process for the preparation of benzene compounds BAYER AKTIENGESELLSCHAFT (DE) 1985-10-29 US disclosed
EP-0091383-A1 Process for the catalytic reduction of nitro-aromatic compounds Montedison S.p.A. (IT) 1983-10-12 EP disclosed
US-4375559-A CATALYTIC HYDROGENATION OF NITRO-ALKYLBENZENES AIR PRODUCTS AND CHEMICALS, INC. (US) 1983-03-01 US disclosed
US-4345978-A Method and apparatus for preparing aromatic hydrazo or diaminodiphenyl compounds BORMA B.V. (NL) 1982-08-24 US disclosed
US-4075198-A PROCESS FOR MANUFACTURE OF BENZIDINE PIGMENTS COLOUR-CHEM LTD. (IN) 1978-02-21 US disclosed
US-3987234-A ACRYLIC ESTER POLYMERS HENKEL & CIE G.M.B.H. (DT) 1976-10-19 US disclosed
US-3917701-A Reduction of certain 2,2{40 -disubstituted azoxybenzenes and azobenzenes to corresponding hydrazobenzenes LOMAC, INC. 1975-11-04 US disclosed