Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958295 | 0.88 | IL1RN (0.37) | ADRB3 | |
| SCHEMBL958294 | 0.88 | IL1RN (0.37) | ADRB3 | |
| SCHEMBL935823 | 0.87 | ECE1 (0.45) | — | |
| SCHEMBL1055434 | 0.87 | ECE1 (0.45) | — | |
| SCHEMBL1045846 | 0.87 | ECE1 (0.45) | — | |
| SCHEMBL935825 | 0.87 | ECE1 (0.45) | — | |
| SCHEMBL937269 | 0.86 | POLB (0.36) | ALDH1A1LMNAADRB3 | |
| SCHEMBL937268 | 0.86 | POLB (0.36) | ALDH1A1LMNAADRB3 | |
| SCHEMBL1052259 | 0.85 | ACE (0.41) | — | |
| SCHEMBL935380 | 0.85 | ACE (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |