Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | ECE1 | P42892 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958295 | 1.00 | IL1RN (0.37) | IL1RNPOLBGFERGPR84ERAP2 | |
| SCHEMBL936769 | 0.92 | CYP3A4 (0.48) | IL1RNERAP2ECE1CYP3A4MAPK1 | |
| SCHEMBL936768 | 0.92 | CYP3A4 (0.48) | IL1RNERAP2ECE1CYP3A4MAPK1 | |
| SCHEMBL937269 | 0.89 | POLB (0.36) | POLBGFERGPR84ECE1ANPEP | |
| SCHEMBL937268 | 0.89 | POLB (0.36) | POLBGFERGPR84ECE1ANPEP | |
| SCHEMBL1055434 | 0.89 | ECE1 (0.45) | POLBERAP2ECE1ITGB2ICAM1 | |
| SCHEMBL935823 | 0.89 | ECE1 (0.45) | POLBERAP2ECE1ITGB2ICAM1 | |
| SCHEMBL1045846 | 0.89 | ECE1 (0.45) | POLBERAP2ECE1ITGB2ICAM1 | |
| SCHEMBL935825 | 0.89 | ECE1 (0.45) | POLBERAP2ECE1ITGB2ICAM1 | |
| SCHEMBL935541 | 0.88 | METAP2 (0.42) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |