Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 14/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 7/20 | 1.00 |
| ▸ | ACP1 | P24666 | 5/20 | 1.00 |
| ▸ | DUSP3 | P51452 | 11/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 9/20 | 0.45 |
| ▸ | CDC25C | P30307 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963589 | 0.80 | CDC25B (1.00) | CDC25BPTPN1ACP1DUSP3HPSE | |
| SCHEMBL935543 | 0.78 | PTPN1 (0.63) | CDC25BPTPN1ACP1HPSEMAPT | |
| SCHEMBL4403663 | 0.73 | CDC25B (1.00) | CDC25BPTPN1ACP1DUSP3HPSE | |
| SCHEMBL1030268 | 0.73 | CDC25B (1.00) | CDC25BPTPN1ACP1DUSP3HPSE | |
| SCHEMBL28550801 | 0.72 | CDC25B (0.97) | CDC25BPTPN1ACP1DUSP3HPSE | |
| SCHEMBL19757457 | 0.72 | L3MBTL1 (0.69) | MAPTTDP1 | |
| SCHEMBL19757418 | 0.72 | L3MBTL1 (0.69) | MAPTTDP1 | |
| SCHEMBL19757415 | 0.72 | L3MBTL1 (0.69) | MAPTTDP1 | |
| SCHEMBL19757451 | 0.72 | L3MBTL1 (0.69) | MAPTTDP1 | |
| SCHEMBL19757417 | 0.72 | L3MBTL1 (0.69) | MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668959-B2 | A3 adenosine receptor ligands for modulation of pigmentation | ORADIN PHARMACEUTICAL LTD. (IL) | 2017-06-06 | — | — | US | disclosed |
| EP-2456419-B1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | ORADIN PHARMACEUTICAL LTD (IL) | 2016-11-23 | — | — | EP | disclosed |
| US-20160136079-A1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | ORADIN PHARMACEUTICAL LTD. (IL) | 2016-05-19 | — | — | US | disclosed |
| US-9199102-B2 | A3 adenosine receptor ligands for modulation of pigmentation | ORADIN PHARMACEUTICAL LTD. (IL) | 2015-12-01 | — | — | US | disclosed |
| US-20120134945-A1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | ORADIN PHARMACEUTICAL LTD. (IL) | 2012-05-31 | — | — | US | disclosed |
| EP-2456419-A1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | Oradin Pharmaceutical Ltd. (IL) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011010306-A1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2011-01-27 | — | — | WO | disclosed |
| US-7019029-B2 | Skin whiteners containing hydroxytetronic acid derivatives | THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT | 2006-03-28 | — | — | US | disclosed |
| US-20020141956-A1 | Skin whiteners containing hydroxytetronic acid derivatives | THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020141956-A1 | Skin whiteners containing hydroxytetronic acid derivatives | TYR, PPP6C, CYP26A1 | CDC25B 2448/4885PTPN1 77/4885ACP1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.