Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354326 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9351018 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9352160 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9351031 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9351142 | 0.99 | ITGB3 (0.42) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9354817 | 0.99 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9351678 | 0.99 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9352209 | 0.99 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9355028 | 0.99 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL9351203 | 0.99 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410756-B1 | Cyclohexenylethane compounds | CHISSO CORP (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5064565-A | Liquid crystals | CHISSO CORPORATION (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0410756-A1 | Cyclohexenylethane compounds | Chisso Corporation (JP) | 1991-01-30 | — | — | EP | disclosed |