Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931349 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL8712755 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL8604452 | 0.71 | KDM4E (0.36) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9359007 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL12919878 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL1877529 | 0.66 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL10667247 | 0.65 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL28244029 | 0.65 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL23141274 | 0.65 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL26696056 | 0.65 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619734-A1 | NEW PHARMACEUTICAL FORMULATIONS OF 5-(2-CHLORO-1-HYDROXYETHYL)-4-METHYLTHIAZOLE | Astra Aktiebolag (SE) | 1994-10-19 | — | — | EP | claimed |
| WO-1992003134-A1 | NEW PHARMACEUTICAL FORMULATIONS OF 5-(2-CHLORO-1-HYDROXYETHYL)-4-METHYLTHIAZOLE | AKTIEBOLAGET ASTRA (SE) | 1992-03-05 | — | — | WO | claimed |