Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571572 | 0.84 | PSMB8 (0.56) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL934808 | 0.78 | PSMB8 (0.56) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL23452413 | 0.77 | PSMB8 (1.00) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL10574548 | 0.74 | PSMB8 (0.65) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL30874518 | 0.68 | PSMB8 (0.67) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL28849254 | 0.68 | PSMB8 (0.67) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL935534 | 0.68 | PSMB8 (0.45) | PSMB8HPGDDYRK1A | |
| SCHEMBL5030198 | 0.67 | PSMB8 (0.65) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL441613 | 0.67 | PSMB8 (0.65) | PSMB8MAPTMEN1KMT2ALMNA | |
| SCHEMBL12312793 | 0.64 | PSMB8 (0.41) | PSMB8MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454329-B1 | FLUORESCENT DYES AND USES THEREOF | BECKMAN COULTER INC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-2454329-B1 | FLUORESCENT DYES AND USES THEREOF | BECKMAN COULTER INC (US) | 2018-04-18 | — | — | EP | disclosed |
| US-8772501-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772501-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772501-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130131324-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131324-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131324-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-8367842-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367842-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367842-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| EP-2454329-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | Beckman Coulter, Inc. (US) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011008912-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | WO | disclosed |
| WO-2011008912-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20110014599-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| US-20110014599-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| US-20110014599-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131324-A1 | Novel Fluorescent Dyes and Uses Thereof | GUSB, CHLSN, NQO1 | PSMB8 4479/4885MAPT 4168/4885MEN1 1205/4885 |
| US-20110014599-A1 | Novel Fluorescent Dyes and Uses Thereof | GUSB, CHLSN, NQO1 | PSMB8 4479/4885MAPT 4168/4885MEN1 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.