SCHEMBL5030198

SCHEMBL5030198

N#Cc1nc2c(S)cccc2s1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 2/20 0.65
ALDH1A1 P00352 9/20 0.39
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
GAA P10253 5/20 0.39
HPGD P15428 4/20 0.39
LMNA P02545 4/20 0.39
KDM4E B2RXH2 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
PRNP P04156 1/20 0.39
MAPT P10636 5/20 0.37
PSMD14 O00487 2/20 0.36
COPS5 Q92905 2/20 0.36
MAPK1 P28482 3/20 0.33
PKM P14618 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
DUSP3 P51452 1/20 0.33
PDPK1 O15530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6465981 0.82 PSMB8 (0.44) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL30874518 0.80 PSMB8 (0.67) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL28849254 0.80 PSMB8 (0.67) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL7902133 0.79 PSMB8 (0.65) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL441613 0.79 PSMB8 (0.65) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL23452413 0.79 PSMB8 (1.00) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL10574548 0.79 PSMB8 (0.65) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL2381198 0.76 PSMB8 (0.56) PSMB8ALDH1A1MEN1KMT2AHPGD
SCHEMBL3067465 0.75 PSMD14 (0.42) PSMB8ALDH1A1MEN1KMT2AGAA
SCHEMBL11709639 0.75 PSMB8 (0.59) PSMB8ALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978873-A Preservative composition and application thereof in anti-corrosion high-temperature-resistant coating 陈向坤 2025-05-13 CN claimed
CN-119978873-A Preservative composition and application thereof in anti-corrosion high-temperature-resistant coating 陈向坤 2025-05-13 CN disclosed
EP-1888575-A2 COMPOUNDS FOR MODULATING TRPV3 FUNCTION Hydra Biosciences, Inc. (US) 2008-02-20 EP disclosed
WO-2006122156-A2 COMPOUNDS FOR MODULATING TRPV3 FUNCTION HYDRA BIOSCIENCES, INC. (US) 2006-11-16 WO disclosed