SCHEMBL935575

SCHEMBL935575

Cc1ccc2cc(Br)ccc2n1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.63
KDM4E B2RXH2 2/20 0.59
BACE1 P56817 2/20 0.59
LMNA P02545 1/20 0.59
POLB P06746 1/20 0.59
CASP6 P55212 1/20 0.59
CYP2A6 P11509 1/20 0.43
KDM1A O60341 1/20 0.42
ALDH1A1 P00352 2/20 0.42
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
PTPN1 P18031 1/20 0.41
PSMB5 P28074 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodomethane SCHEMBL28083725 0.96 CYP1A2 (0.59) CYP1A2KDM4EBACE1LMNAPOLB
SCHEMBL2222111 0.84 CYP1A2 (0.61) CYP1A2KDM4EBACE1LMNAPOLB
SCHEMBL30390874 0.84 CYP1A2 (0.61) CYP1A2KDM4EBACE1LMNAPOLB
SCHEMBL14894660 0.78 BACE1 (0.53) CYP1A2KDM4EBACE1LMNAPOLB
SCHEMBL29444268 0.77 CYP1A2 (1.00) CYP1A2KDM4EBACE1LMNAPOLB
SCHEMBL161703 0.77 CYP1A2 (1.00) CYP1A2KDM4EBACE1LMNAPOLB
SCHEMBL7265492 0.77 BACE1 (0.63) CYP1A2KDM4EBACE1POLBCYP2A6
SCHEMBL1914302 0.77 BACE1 (0.63) CYP1A2KDM4EBACE1CYP2A6ALDH1A1
SCHEMBL30527824 0.77 BACE1 (0.63) CYP1A2KDM4EBACE1CYP2A6ALDH1A1
SCHEMBL10259445 0.76 CYP1A2 (0.68) CYP1A2KDM4ELMNAPOLBCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707791-A Double-response fluorescent probe for simultaneously imaging myelin and Abeta aggregates in AD brain, and preparation method and application thereof 南京师范大学 2025-03-28 CN claimed
CN-115947720-B Design, preparation and application of beta 3 adrenergic receptor anchoring probe 南京师范大学 2024-03-29 CN claimed
CN-115947720-A Design of beta 3 adrenergic receptor anchoring probe and preparation method and application thereof 南京师范大学 2023-04-11 CN claimed
CN-114426534-B Reversible fluorescent probe for detecting copper ions and preparation method thereof 南京师范大学 2023-01-31 CN claimed
CN-114426534-A Reversible fluorescent probe for detecting copper ions and preparation method thereof 南京师范大学 2022-05-03 CN claimed
CN-109111397-B Quinoline aromatic ethylene derivative and preparation method and application thereof 广东工业大学 2021-12-10 CN claimed
CN-113754583-A 2- ([2, 2' -biquinolyl ] -3-ether) -1-ethanol and derivative and synthetic method thereof 湖南工程学院 2021-12-07 CN claimed
CN-110606839-B Green synthesis method of polysubstituted quinazoline derivative 南方医科大学 2021-10-08 CN claimed
CN-109111396-B Quinoline aromatic vinyl derivative and preparation method and application thereof 广东工业大学 2021-09-03 CN claimed
CN-113234067-A 2, 5-disubstituted thiophene compounds and synthetic method thereof 湘潭大学 2021-08-10 CN claimed
CN-112979619-A Method for catalyzing dehydrogenation coupling reaction of nitrogen heteroaromatic ring compound and cyclic ether by using Bronsted acid 青岛职业技术学院 2021-06-18 CN claimed
CN-109776406-B Method for cross coupling of ether compound and quinoline derivative 湘潭大学 2021-05-04 CN claimed
CN-104447539-B A kind of two grades, the synthetic method of three-level aromatic amides 湖南大学 2017-09-15 CN claimed
CN-106565600-A Deuterated aza aromatic compound and synthesis method thereof 湖南大学 2017-04-19 CN claimed
CN-104447539-A Method for synthesizing binary and ternary aryl amide compounds UNIV HUNAN 2015-03-25 CN claimed
CN-104447540-A Synthetic method of primary aryl amide compounds UNIV HUNAN 2015-03-25 CN claimed
CN-101591291-B Synthesis method of 2-ethenyl quinoline compound INST MATERIA MEDICA CAMS 2012-07-18 CN claimed
CN-101591291-A The synthetic method of 2-ethenyl quinoline compound INST MATERIA MEDICA CAMS (CN) 2009-12-02 CN claimed
US-20260138998-A1 GLP-1 RECEPTOR AGONISTS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-05-21 US disclosed
EP-0014929-A1 Diagnostic means, process for its preparation and its use in determining leucocytes in body fluids Roche Diagnostics GmbH (DE) 1980-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138998-A1 GLP-1 RECEPTOR AGONISTS AND METHODS OF USE GLP1R, GIPR, GPR119 CYP1A2 2666/4885KDM4E 2314/4885BACE1 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.