Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268616 | 0.86 | GRIN2D (0.45) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1994831 | 0.84 | TDP1 (0.41) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL391249 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10701814 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31569256 | 0.82 | GRIN2D (0.41) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL32659684 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL25786773 | 0.76 | ALDH1A1 (0.37) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31569422 | 0.76 | MAPT (0.43) | ALDH1A1MEN1KMT2ANPC1LMNA | |
| SCHEMBL12326844 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL20810981 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682961-A | Preparation method of 4,4' -diamino-2, 2-bistrifluoromethyl biphenyl | 山东省晨宏化工科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-114635037-B | Method for extracting and separating trivalent lanthanide and/or trivalent actinide | 浙江大学 | 2022-11-25 | — | — | CN | claimed |
| CN-115228417-A | Synthesis device and synthesis method of m-nitrobenzotrifluoride | 福建康峰新材料有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-113024385-B | Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl | 西安瑞联新材料股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-114635037-A | Method for extracting and separating trivalent lanthanide and/or trivalent actinide | 浙江大学 | 2022-06-17 | — | — | CN | claimed |
| CN-112458283-B | Phenanthroline phosphorus oxide and method for extracting and separating trivalent lanthanide and/or actinide ions | 浙江大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113045425-A | Method for preparing 2,2 '-bis (trifluoromethyl) -4, 4' -dinitrobiphenyl | 天津市泰合利华材料科技有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-113024385-A | Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl | 西安瑞联新材料股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-111434785-B | Extraction method, back extraction method, complex and extraction system | 清华大学 | 2021-03-19 | — | — | CN | claimed |
| CN-112458283-A | Phenanthroline phosphorus oxide and method for extracting and separating trivalent lanthanide and/or actinide ions | 浙江大学 | 2021-03-09 | — | — | CN | claimed |
| CN-111434785-A | Extraction method, back extraction method, complex and extraction system | 清华大学 | 2020-07-21 | — | — | CN | claimed |
| CN-108026610-B | Method for separating americium from liquid radioactive substances and separating americium from rare earth elements | 俄罗斯国家原子能公司 | 2020-05-12 | — | — | CN | claimed |
| CN-115724745-A | Preparation method of 4,4 '-diamino-2, 2' -bistrifluoromethylbiphenyl | 沈阳化工研究院有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-114635037-B | Method for extracting and separating trivalent lanthanide and/or trivalent actinide | 浙江大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-115124430-A | Synthesis process of 2,2' -bis (trifluoromethyl) diaminobiphenyl | 苏利制药科技江阴有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-113117376-B | Phenanthroline derivative extracting agent and preparation method and application thereof | 中国科学院高能物理研究所 | 2022-08-19 | — | — | CN | disclosed |
| WO-2011009814-A1 | COMPOUNDS SUITABLE FOR USE AS ACTINIDE LIGANDS, SYNTHESIS AND USES THEREOF | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2011-01-27 | — | — | WO | disclosed |
| CN-101891626-A | Solvent-free hydrogenation reduction process with halogen nitrobenzene or without halogen nitrobenzene | HONGYUN LI | 2010-11-24 | — | — | CN | disclosed |
| US-20050009898-A1 | New substituted indolinones, their manufacture and their use as medicaments | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-13 | — | — | US | disclosed |
| US-6794395-B1 | Substituted indolinones, their manufacture and their use as medicaments | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009898-A1 | New substituted indolinones, their manufacture and their use as medicaments | CCNE1, CDK1, CCNI | ALDH1A1 1840/4885TDP1 1972/4885GRIN2D 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.