Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352549 | 1.00 | CHRM2 (0.50) | CHRM2CHRM4CHRM5GRM6S1PR5 | |
| SCHEMBL29142190 | 0.89 | GRM6 (0.49) | CHRM2CHRM4CHRM5GRM6S1PR5 | |
| SCHEMBL27089262 | 0.89 | GRM6 (0.49) | CHRM2CHRM4CHRM5GRM6S1PR5 | |
| SCHEMBL27089432 | 0.89 | GRM6 (0.49) | CHRM2CHRM4CHRM5GRM6S1PR5 | |
| SCHEMBL4710674 | 0.89 | GRM6 (0.49) | CHRM2CHRM4CHRM5GRM6S1PR5 | |
| SCHEMBL4710677 | 0.89 | GRM6 (0.49) | CHRM2CHRM4CHRM5GRM6S1PR5 | |
| SCHEMBL5451605 | 0.87 | CYP3A4 (0.54) | KMT2AL3MBTL1 | |
| SCHEMBL9352245 | 0.87 | CYP3A4 (0.54) | KMT2AL3MBTL1 | |
| SCHEMBL5458626 | 0.87 | CYP3A4 (0.54) | KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15662362 | 0.87 | CHRM2 (0.49) | CHRM2CHRM4CHRM5GRM6S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603683-A | Substituted phenyl oxazolidinones for antimicrobial therapy | 结核病药物开发全球联盟公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-108348507-B | Substituted phenyl oxazolidinones for antimicrobial therapy | 结核病药物开发全球联盟公司 | 2021-10-08 | — | — | CN | disclosed |
| EP-0299513-B1 | Azetidine derivatives, compositions and their use | FIDIA GEORGETOWN INST (US) | 1994-10-05 | — | — | EP | disclosed |
| US-4990504-A | Modulate excitatory amino acid receptor system | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1991-02-05 | — | — | US | disclosed |
| US-4946839-A | ALZHEIMER'S DISEASE | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0299513-A1 | Azetidine derivatives, compositions and their use | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1989-01-18 | — | — | EP | disclosed |