SCHEMBL9356337

SCHEMBL9356337

CCCC(C)(C)NNC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
ADRA1A P35348 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355326 0.84 MEN1 (0.39) FDPS
SCHEMBL9352362 0.82 EPHX1 (0.33)
SCHEMBL9484958 0.77 ALDH1A1 (0.57) ALDH1A1LMNAHSD17B10TSHRCYP3A4
Hydrochloric Acid SCHEMBL21990280 0.72 ALDH1A1 (0.39) ALDH1A1TSHRCYP3A4TDP1
SCHEMBL2699370 0.71
SCHEMBL15131256 0.70 CNR2 (0.31)
Butyric Acid SCHEMBL28597114 0.69 FFAR3 (0.50) ALDH1A1HSD17B10TSHRTDP1
SCHEMBL15131399 0.67 CRBN (0.32) LMNATSHRCYP3A4NFKB1
SCHEMBL277242 0.66
SCHEMBL22851721 0.65 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392233-B1 Substituted 1,2,3,4,-Oxatriazolium-5-olates, method for their preparation and their use CASSELLA FARBWERKE MAINKUR AG (DE) 1994-09-21 EP disclosed
US-5091398-A Antianginal, antithrombotic CASSELLA AKTIENGELLSCHAFT (DE) 1992-02-25 US disclosed
EP-0392233-A1 Substituted 1,2,3,4,-Oxatriazolium-5-olates, method for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1990-10-17 EP disclosed