Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.86 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.86 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.86 |
| ▸ | KDR | P35968 | 3/20 | 0.86 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.86 |
| ▸ | MMP2 | P08253 | 3/20 | 0.65 |
| ▸ | MMP9 | P14780 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | APC | P25054 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212856 | 0.91 | EGFR (0.75) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL31429976 | 0.91 | EGFR (0.75) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL25138590 | 0.88 | EGFR (0.78) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL11208392 | 0.85 | EGFR (0.74) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL27760024 | 0.85 | EGFR (0.74) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL9568963 | 0.83 | EGFR (1.00) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL11210797 | 0.82 | EGFR (0.74) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL11205361 | 0.82 | EGFR (0.74) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL27955202 | 0.82 | MEN1 (0.77) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL13680428 | 0.80 | EGFR (0.94) | EGFRERBB2ERBB3KDRPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451561-B1 | Photopolymerisable mixture and recording material made from it | MORTON INT INC (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5221595-A | Printing plates, photoresist; high photosensitivity, acid resistance | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0451561-A1 | Photopolymerisable mixture and recording material made from it | MORTON INTERNATIONAL, INC. (US) | 1991-10-16 | — | — | EP | disclosed |