SCHEMBL9356808

SCHEMBL9356808

OCC(CBr)(CCBr)CCBr

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
TSHR P16473 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681303 0.87 TSHR (0.53) ALDH1A1TSHR
SCHEMBL7608435 0.87 TSHR (0.53) ALDH1A1TSHR
SCHEMBL5909183 0.79 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL942604 0.79
SCHEMBL229830 0.79
SCHEMBL27976852 0.79 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL399680 0.79
Bromide SCHEMBL8138714 0.73 ALDH1A1 (0.86) ALDH1A1TSHR
SCHEMBL6199661 0.73 ALDH1A1 (0.52) ALDH1A1TSHR
SCHEMBL6338979 0.71 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103221404-B Can be used as the unsaturated nitrogen heterogeneous ring compound of PDE10 inhibitor AMGEN INC. (US) 2015-12-16 CN disclosed
EP-0472492-B1 Tris-perfluoroalkyl terminated neopentyl alcohols and derivatives therefrom CIBA GEIGY AG (CH) 1994-10-05 EP disclosed
EP-0472492-A1 Tris-perfluoroalkyl terminated neopentyl alcohols and derivatives therefrom CIBA-GEIGY AG (CH) 1992-02-26 EP disclosed