Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357214 | 0.92 | ABCB1 (0.46) | ABCB1ESR1ESR2 | |
| SCHEMBL9356905 | 0.89 | ESR1 (0.40) | TDP1KCNK3ABCB1KCNK9ESR1 | |
| SCHEMBL9356940 | 0.89 | ESR1 (0.40) | HPGDTDP1KCNK3ABCB1KCNK9 | |
| SCHEMBL9356794 | 0.89 | ABCB1 (0.42) | HPGDKCNK3ABCB1KCNK9ESR1 | |
| SCHEMBL9356985 | 0.89 | HPGD (0.39) | HPGDTDP1KCNK3ABCB1KCNK9 | |
| SCHEMBL9356888 | 0.89 | KCNK3 (0.41) | HPGDTDP1KCNK3ABCB1KCNK9 | |
| SCHEMBL9356783 | 0.89 | HPGD (0.39) | HPGDTDP1KCNK3ABCB1KCNK9 | |
| SCHEMBL9356789 | 0.89 | HPGD (0.39) | HPGDTDP1KCNK3ABCB1KCNK9 | |
| SCHEMBL9357291 | 0.87 | ABCB1 (0.50) | KCNK3ABCB1KCNK9NPC1RAB9A | |
| SCHEMBL9356844 | 0.85 | ESR1 (0.37) | ABCB1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | claimed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | claimed |
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | disclosed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | disclosed |