Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356842 | 0.92 | ABCB1 (0.45) | ABCB1 | |
| SCHEMBL9357142 | 0.91 | LMNA (0.41) | HPGDTDP1ABCB1NPC1LMNA | |
| SCHEMBL9360864 | 0.90 | CTSS (0.35) | ABCB1POLB | |
| SCHEMBL9356941 | 0.89 | HPGD (0.40) | HPGDTDP1ABCB1NPC1RAB9A | |
| SCHEMBL9357187 | 0.88 | ABCB1 (0.35) | ABCB1THRBRXFP1 | |
| SCHEMBL9356888 | 0.87 | KCNK3 (0.41) | HPGDTDP1ABCB1NPC1LMNA | |
| SCHEMBL9356783 | 0.87 | HPGD (0.39) | HPGDTDP1ABCB1NPC1RAB9A | |
| SCHEMBL9854889 | 0.84 | KCNK3 (0.45) | HPGDTDP1ABCB1NPC1LMNA | |
| SCHEMBL9356802 | 0.83 | ABCB1 (0.40) | ABCB1 | |
| SCHEMBL9356794 | 0.82 | ABCB1 (0.42) | HPGDABCB1SMN1; SMN2KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | claimed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | claimed |