Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357480 | 1.00 | RAB9A (0.44) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9361721 | 0.99 | RAB9A (0.44) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9357742 | 0.95 | RAB9A (0.45) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9361368 | 0.93 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9361463 | 0.93 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9819418 | 0.93 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9357759 | 0.93 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL10346199 | 0.92 | RAB9A (0.55) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL9235695 | 0.92 | RAB9A (0.55) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL10705787 | 0.88 | NPC1 (0.55) | RAB9ASMN1; SMN2MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289270-B1 | Optically active 2-biphenylpyrimidine derivatives and liquid crystal compositions containing them | CHISSO CORP (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5059340-A | For display mode | CHISSO CORPORATION (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0289270-A1 | Optically active 2-biphenylpyrimidine derivatives and liquid crystal compositions containing them | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |