Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.34 |
| ▸ | COMT | P21964 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664988 | 0.81 | COMT (0.40) | TYRCOMT | |
| SCHEMBL12968429 | 0.79 | TYR (0.38) | TYRCOMT | |
| SCHEMBL9357297 | 0.79 | TYR (0.34) | TYRCOMT | |
| SCHEMBL15991636 | 0.78 | CCNC (0.49) | TYRCCNCCDK8 | |
| SCHEMBL13451741 | 0.75 | TYR (0.35) | TYRCOMT | |
| SCHEMBL20125111 | 0.75 | FFAR1 (0.41) | TYRCOMT | |
| SCHEMBL13467618 | 0.75 | TYR (0.42) | TYRCOMT | |
| SCHEMBL15680210 | 0.75 | TYR (0.35) | TYRCOMT | |
| SCHEMBL15680165 | 0.72 | TYR (0.33) | TYRCOMT | |
| SCHEMBL15680168 | 0.70 | TYR (0.32) | TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289002-B1 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0209751-B1 | CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4758557-A | Cephalosporin derivatives and bactericides containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0209751-A2 | Cephalosporin derivatives and bactericides containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1987-01-28 | — | — | EP | disclosed |