Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DBH | P09172 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 3/20 | 0.35 |
| ▸ | COMT | P21964 | 4/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968429 | 0.79 | TYR (0.38) | TYRCOMTCYP3A4HPGD | |
| SCHEMBL17191827 | 0.77 | MAPT (0.47) | TYRALDH1A1MAPT | |
| SCHEMBL9664988 | 0.76 | COMT (0.40) | TYRCOMT | |
| SCHEMBL19425992 | 0.75 | ALDH1A1 (0.38) | TYRCOMTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9357297 | 0.75 | TYR (0.34) | TYRCOMT | |
| SCHEMBL9357301 | 0.75 | TYR (0.34) | TYRCOMT | |
| SCHEMBL13451741 | 0.74 | TYR (0.35) | TYRCOMTHDAC4HDAC2HDAC8 | |
| SCHEMBL13467618 | 0.74 | TYR (0.42) | TYRCOMTCYP3A4CA9 | |
| SCHEMBL15680210 | 0.74 | TYR (0.35) | TYRCOMT | |
| SCHEMBL17191934 | 0.73 | COMT (0.49) | KDM4ETYRCOMTMDM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2706062-B1 | NOVEL CEPHALOSPORIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | LEGOCHEM BIOSCIENCES INC (KR) | 2018-05-09 | — | — | EP | disclosed |