SCHEMBL9357474

SCHEMBL9357474

C=CCc1cc(C)ccc1OCC1CO1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
GLA P06280 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
GAA P10253 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
TP53 P04637 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
HIF1A Q16665 1/20 0.40
PTGDR Q13258 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
TDP1 Q9NUW8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10636761 0.86 ALDH1A1 (0.43) ALDH1A1GLAL3MBTL1SMN1; SMN2LMNA
SCHEMBL17145784 0.86 CNR2 (0.43) ALDH1A1GLASMN1; SMN2TP53CYP3A4
SCHEMBL15814632 0.86 CNR2 (0.43) ALDH1A1GLASMN1; SMN2TP53CYP3A4
SCHEMBL17055414 0.86 CNR2 (0.43) ALDH1A1GLASMN1; SMN2TP53CYP3A4
SCHEMBL16828372 0.84 ALDH1A1 (0.51) ALDH1A1GLAL3MBTL1SMN1; SMN2LMNA
SCHEMBL22289405 0.84 ALDH1A1 (0.54) ALDH1A1GLASMN1; SMN2LMNAMAPT
SCHEMBL11594847 0.84 MAPT (0.53) ALDH1A1GLAL3MBTL1SMN1; SMN2LMNA
SCHEMBL18593749 0.84 ALDH1A1 (0.45) ALDH1A1GLASMN1; SMN2LMNAMAPT
SCHEMBL19104728 0.83 CNR2 (0.41) ALDH1A1GLASMN1; SMN2TP53CYP3A4
SCHEMBL11590992 0.83 PTGDR (0.56) ALDH1A1GLASMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376444-B1 A thermosetting organic composition FORD MOTOR CO (GB) 1994-12-07 EP disclosed
US-5183865-A Thermosettable powder compositions of polymaleimide and allyl-functional prepolymer FORD MOTOR COMPANY (US) 1993-02-02 US disclosed
EP-0376444-A2 A thermosetting organic composition FORD MOTOR COMPANY LIMITED (GB) 1990-07-04 EP disclosed