Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358560 | 0.88 | HRH2 (0.59) | HRH2HRH3 | |
| SCHEMBL9362673 | 0.87 | HRH2 (0.60) | HRH2HRH3 | |
| SCHEMBL9358202 | 0.86 | HRH2 (0.57) | HRH2HRH3 | |
| SCHEMBL9358465 | 0.86 | HRH2 (0.56) | HRH2HRH3 | |
| SCHEMBL9358223 | 0.86 | HRH2 (0.59) | HRH2HRH3 | |
| SCHEMBL9358564 | 0.86 | HRH2 (0.59) | HRH2HRH3 | |
| SCHEMBL9358452 | 0.86 | HRH2 (0.56) | HRH2HRH3 | |
| SCHEMBL9358134 | 0.85 | FAAH (0.62) | HRH2HRH3 | |
| SCHEMBL9362617 | 0.84 | HRH2 (0.57) | HRH2HRH3 | |
| SCHEMBL9362343 | 0.84 | FAAH (0.61) | HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470006-B1 | Thiourea derivatives and antimicrobial agent and antiulcer agent containing the same | TERUMO CORP (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5190961-A | Bactericides | TERUMO KABUSHIKI KAISHA (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0470006-A1 | Thiourea derivatives and antimicrobial agent and antiulcer agent containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1992-02-05 | — | — | EP | disclosed |