Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 6/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935884 | 0.91 | PIK3R1 (0.44) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL5608425 | 0.84 | PIK3CD (0.58) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL935655 | 0.83 | PIK3CD (0.43) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL9924638 | 0.82 | PIK3R1 (0.45) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL9884274 | 0.81 | PIK3R1 (0.42) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL2599465 | 0.81 | PIK3CD (0.41) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL935114 | 0.81 | PIK3CD (0.39) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL5606851 | 0.81 | PIK3CD (0.56) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL936097 | 0.80 | PIK3R1 (0.42) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL935671 | 0.80 | PIK3CD (0.51) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456444-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011008302-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2011-01-20 | — | — | WO | disclosed |
| EP-2240452-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-2240451-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009088986-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009088990-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2009-07-16 | — | — | WO | disclosed |