Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962661 | 0.84 | TOP2B (0.54) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9517779 | 0.77 | MEN1 (0.48) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL30678386 | 0.77 | MEN1 (0.60) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL29366166 | 0.77 | MEN1 (0.60) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL78525 | 0.77 | MEN1 (0.60) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL5695954 | 0.75 | MEN1 (0.55) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL4655713 | 0.74 | MAPT (0.54) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL2421375 | 0.74 | MEN1 (0.54) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL11131632 | 0.74 | POLB (0.63) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL1426702 | 0.74 | TOP2B (0.81) | MEN1KMT2APOLBBLMNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333337-B1 | Thermal transfer sheet | ZENECA LTD (GB) | 1994-12-21 | — | — | EP | disclosed |
| US-5102448-A | Hot melt of solid ink composition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-07 | — | — | US | disclosed |
| US-4933426-A | POLYLACTONE CONTAINING BOUND DYE, WAX REPLACEMENT IN THERMAL WAX TRANSFER | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-12 | — | — | US | disclosed |
| EP-0371627-A2 | Ink-jet printing | ZENECA LIMITED (GB) | 1990-06-06 | — | — | EP | disclosed |
| EP-0333337-A2 | Thermal transfer sheet | ZENECA LIMITED (GB) | 1989-09-20 | — | — | EP | disclosed |