Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358342 | 1.00 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9354175 | 0.96 | KMT2A (0.62) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9354176 | 0.96 | KMT2A (0.62) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9353971 | 0.87 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9353965 | 0.87 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9354000 | 0.80 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3928399 | 0.80 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9354592 | 0.80 | PTGS2 (0.55) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9354586 | 0.80 | PTGS2 (0.55) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9357939 | 0.79 | PTGS2 (0.51) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357783-B1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0357783-A1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |