Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358386 | 1.00 | HTT (0.56) | HTTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1769490 | 0.90 | HTT (0.53) | HTTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1769493 | 0.90 | HTT (0.53) | HTTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1799638 | 0.86 | HTT (0.54) | HTTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1768811 | 0.84 | HTT (0.48) | HTTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1768813 | 0.84 | HTT (0.48) | HTTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23981462 | 0.83 | SMN1; SMN2 (0.64) | HTTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL19115061 | 0.83 | DPP7 (0.42) | HTTKMT2AMEN1TSHRDRD2 | |
| SCHEMBL29220797 | 0.83 | SMN1; SMN2 (0.64) | HTTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL25360385 | 0.83 | DRD2 (0.44) | HTTKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | claimed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | claimed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |