SCHEMBL9358495

SCHEMBL9358495

CC/C=C(/OC(=O)c1ccccc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
TSHR P16473 4/20 0.46
F2 P00734 1/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
TDP1 Q9NUW8 4/20 0.42
SLC6A3 Q01959 2/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
SLC6A2 P23975 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 1/20 0.40
ELANE P08246 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CYP2D6 P10635 2/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28261293 1.00 LMNA (0.47) LMNATSHRF2CES2CES1
SCHEMBL10582288 0.87 LMNA (0.49) LMNATSHRF2CES2CES1
SCHEMBL6862201 0.82 LMNA (0.50) LMNATSHRF2CES2CES1
SCHEMBL10579880 0.82 EP300 (0.46) LMNATSHRCES2CES1ALDH1A1
SCHEMBL10900780 0.81 LMNA (0.49) LMNATSHRF2CES2CES1
SCHEMBL27489702 0.81 LMNA (0.49) LMNATSHRF2CES2CES1
SCHEMBL6551398 0.79 LMNA (0.47) LMNATSHRF2CES2CES1
SCHEMBL27491662 0.79 LMNA (0.47) LMNATSHRF2CES2CES1
SCHEMBL4577714 0.78 LMNA (0.46) LMNATSHRF2CES2CES1
SCHEMBL29189837 0.78 TSHR (0.53) LMNATSHRF2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454379-B1 Thermal transfer image-receiving sheet OJI PAPER CO (JP) 1994-12-07 EP claimed
EP-0300226-A2 Laminate for the formation of beam leads for IC chip bonding EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-01-25 EP disclosed
US-4792517-A METAL STRIP, PHOTORESISTS EASTMAN KODAK COMPANY (US) 1988-12-20 US disclosed