Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582677 | 0.86 | MAPT (0.57) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL10585355 | 0.85 | MEN1 (0.47) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL24497413 | 0.83 | MAPT (0.47) | ALDH1A1TEAD1MEN1KMT2AMAPT | |
| SCHEMBL10586422 | 0.80 | FGFR4 (0.56) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL22719743 | 0.78 | TEAD1 (0.60) | TEAD1MAPTGAAKDR | |
| SCHEMBL9358482 | 0.78 | TEAD1 (0.55) | TEAD1MAPTGAAABL1KDR | |
| SCHEMBL10582412 | 0.78 | MEN1 (0.60) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL25314807 | 0.77 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL22719666 | 0.75 | TEAD1 (0.52) | ALDH1A1TEAD1MEN1KMT2AMAPT | |
| SCHEMBL29505063 | 0.75 | TEAD1 (0.52) | ALDH1A1TEAD1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320448-A2 | 3-Aminobenzoyl phenyl urea | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | claimed |
| EP-0320448-B1 | 3-Aminobenzoyl phenyl urea | CIBA GEIGY AG (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-4946854-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0320448-A2 | 3-Aminobenzoyl phenyl urea | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |