Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.80 |
| ▸ | ESR1 | P03372 | 3/20 | 0.67 |
| ▸ | CES2 | O00748 | 3/20 | 0.59 |
| ▸ | CES1 | P23141 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358575 | 1.00 | PTGS2 (0.80) | PTGS2ESR1CES2CES1ESR2 | |
| SCHEMBL1827643 | 0.91 | PTGS2 (0.74) | PTGS2ESR1CES2CES1ESR2 | |
| SCHEMBL4961440 | 0.89 | PTGS2 (0.71) | PTGS2ESR1CES2CES1ESR2 | |
| SCHEMBL28108412 | 0.89 | PTGS2 (1.00) | PTGS2ESR1ESR2 | |
| SCHEMBL3405445 | 0.87 | PTGS2 (0.69) | PTGS2ESR1CES2CES1ESR2 | |
| SCHEMBL10707754 | 0.86 | PTGS2 (0.67) | PTGS2ESR1CES2CES1ESR2 | |
| SCHEMBL4326009 | 0.85 | ESR1 (0.64) | PTGS2ESR1CES2CES1ESR2 | |
| SCHEMBL15673165 | 0.84 | PTGS2 (0.65) | PTGS2ESR1CES2CES1 | |
| SCHEMBL27820282 | 0.84 | PTGS2 (0.65) | PTGS2ESR1CES2CES1 | |
| SCHEMBL30751176 | 0.83 | PTGS2 (0.63) | PTGS2ESR1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344888-B1 | Liquid telechelic polymers having high 1,4-diene structure | GENCORP INC (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5216181-A | Liquid telechelic polymers having high 1,4-diene structure | GENCORP INC. (US) | 1993-06-01 | — | — | US | disclosed |
| US-5202499-A | Trans configuration, low bulk viscosity | GENCORP INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-5063190-A | Anionic initiator system for polymerizing monomers | GENCORP INC. (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0344888-A2 | Liquid telechelic polymers having high 1,4-diene structure | GENCORP INC. (US) | 1989-12-06 | — | — | EP | disclosed |
| US-3946081-A | OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |