SCHEMBL9359003

SCHEMBL9359003

COc1cc2cc(S(=O)(=O)O)ccc2cc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 2/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
CASP6 P55212 1/20 0.51
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
F2 P00734 3/20 0.46
PRSS1 P07477 3/20 0.46
PRSS2 P07478 3/20 0.46
PRSS3 P35030 3/20 0.46
SNCA P37840 2/20 0.44
CYP1A2 P05177 1/20 0.43
PKM P14618 1/20 0.42
ENPP2 Q13822 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4017803 0.89 SNCA (0.50) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL4016326 0.87 SNCA (0.49) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL7692151 0.83 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL11038510 0.82 ALDH1A1 (0.49) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL155420 0.82 MAPT (0.54) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL155353 0.82 CA1 (0.68) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL30556228 0.82 MAPT (0.54) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL14988893 0.82 MAPT (0.54) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL14988995 0.80 CA1 (0.66) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL9817020 0.80 CA1 (0.66) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0474039-B1 Ortho-aminoazo compounds BAYER AG (DE) 1994-11-09 EP disclosed
US-5183881-A Chemical intermediate for metallized dyes BAYER AKTIENGESELLSCHAFT (DE) 1993-02-02 US disclosed
EP-0474039-A1 Ortho-aminoazo compounds BAYER AG (DE) 1992-03-11 EP disclosed